Entity Details

Primary name PRKAA1
Entity type gene
Source Source Link

Details

PrimaryID5562
RefseqGene
SymbolPRKAA1
Nameprotein kinase AMP-activated catalytic subunit alpha 1
Chromosome5
Location5p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-06-24
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsAAPK1_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001666 response to hypoxia
GO:0003682 chromatin binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004679 AMP-activated protein kinase activity
GO:0004691 cAMP-dependent protein kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006006 glucose metabolic process
GO:0006468 protein phosphorylation
GO:0006633 fatty acid biosynthetic process
GO:0006695 cholesterol biosynthetic process
GO:0007165 signal transduction
GO:0008022 protein C-terminus binding
GO:0008284 positive regulation of cell population proliferation
GO:0008610 lipid biosynthetic process
GO:0009411 response to UV
GO:0009631 cold acclimation
GO:0010332 response to gamma radiation
GO:0010508 positive regulation of autophagy
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0014823 response to activity
GO:0015721 bile acid and bile salt transport
GO:0016055 Wnt signaling pathway
GO:0016236 macroautophagy
GO:0016241 regulation of macroautophagy
GO:0016324 apical plasma membrane
GO:0016607 nuclear speck
GO:0019395 fatty acid oxidation
GO:0030424 axon
GO:0030425 dendrite
GO:0031000 response to caffeine
GO:0031588 nucleotide-activated protein kinase complex
GO:0031669 cellular response to nutrient levels
GO:0032007 negative regulation of TOR signaling
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0034599 cellular response to oxidative stress
GO:0035174 histone serine kinase activity
GO:0035556 intracellular signal transduction
GO:0035690 cellular response to drug
GO:0038183 bile acid signaling pathway
GO:0042149 cellular response to glucose starvation
GO:0042593 glucose homeostasis
GO:0042752 regulation of circadian rhythm
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0044877 protein-containing complex binding
GO:0045542 positive regulation of cholesterol biosynthetic process
GO:0045821 positive regulation of glycolytic process
GO:0046318 negative regulation of glucosylceramide biosynthetic process
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0046872 metal ion binding
GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
GO:0048156 tau protein binding
GO:0048511 rhythmic process
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0050321 tau-protein kinase activity
GO:0050405 [acetyl-CoA carboxylase] kinase activity
GO:0050995 negative regulation of lipid catabolic process
GO:0055089 fatty acid homeostasis
GO:0060627 regulation of vesicle-mediated transport
GO:0061744 motor behavior
GO:0061762 CAMKK-AMPK signaling cascade
GO:0062028 regulation of stress granule assembly
GO:0070050 neuron cellular homeostasis
GO:0070301 cellular response to hydrogen peroxide
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0071277 cellular response to calcium ion
GO:0071333 cellular response to glucose stimulus
GO:0071361 cellular response to ethanol
GO:0071380 cellular response to prostaglandin E stimulus
GO:0071417 cellular response to organonitrogen compound
GO:0071456 cellular response to hypoxia
GO:0097009 energy homeostasis
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120188 regulation of bile acid secretion
GO:1901563 response to camptothecin
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1903109 positive regulation of mitochondrial transcription
GO:1903829 positive regulation of cellular protein localization
GO:1903955 positive regulation of protein targeting to mitochondrion
GO:1904428 negative regulation of tubulin deacetylation
GO:1904486 response to 17alpha-ethynylestradiol
GO:2000758 positive regulation of peptidyl-lysine acetylation

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
PRKAA1Sde2BioGRID, IntAct20368287 details
PRKAA1Mtfr2BioGRID, IntAct20368287 details
PRKAA1Xrn2BioGRID, IntAct20368287 details
PRKAA1Abi1BioGRID, IntAct20368287 details
PRKAA1AprtBioGRID, IntAct20368287 details
PRKAA1Prkag2BioGRID, IntAct20368287 details
PRKAA1Bhlhe40BioGRID, IntAct20368287 details
PRKAA1CherpBioGRID, IntAct20368287 details
PRKAA1CpeBioGRID, IntAct20368287 details
PRKAA1Emilin1BioGRID, IntAct20368287 details
PRKAA1GrnBioGRID, IntAct20368287 details
PRKAA1Arhgap22BioGRID, IntAct20368287 details
PRKAA1Hspb1BioGRID, IntAct20368287 details
PRKAA1Kif1cBioGRID, IntAct20368287 details
PRKAA1Lzts2BioGRID, IntAct20368287 details
PRKAA1Maged1BioGRID, IntAct20368287 details
PRKAA1Nedd1BioGRID, IntAct20368287 details
PRKAA1Nab2BioGRID, IntAct20368287 details
PRKAA1Nrbf2BioGRID, IntAct20368287 details
PRKAA1Prkab1BioGRID, IntAct20368287 details
PRKAA1Rc3h1BioGRID, IntAct20368287 details
PRKAA1Sorbs1BioGRID, IntAct20368287 details
PRKAA1TfptBioGRID, IntAct20368287 details
PRKAA1Thap7BioGRID, IntAct20368287 details
PRKAA1Trip6BioGRID, IntAct20368287 details
PRKAA1Crtc2DIP18626018 details
PRKAA1Prkag1BioGRID20368287 details
PRKAA1Trp53BioGRID15866171 details
PRKAA1PpardIntAct18674809 details
PRKAA1NcstnBioGRID, IntAct26496610 details
PRKAA1CitBioGRID26496610 details