Entity Details

Primary name VPS35
Entity type gene
Source Source Link

Details

PrimaryID55737
RefseqGeneNG_029970
SymbolVPS35
NameVPS35 retromer complex component
Chromosome16
Location16q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-10-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsVPS35_HUMAN

GO terms

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GOName
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005829 cytosol
GO:0006886 intracellular protein transport
GO:0010008 endosome membrane
GO:0010628 positive regulation of gene expression
GO:0010821 regulation of mitochondrion organization
GO:0016032 viral process
GO:0016055 Wnt signaling pathway
GO:0016241 regulation of macroautophagy
GO:0030904 retromer complex
GO:0030906 retromer, cargo-selective complex
GO:0031647 regulation of protein stability
GO:0031748 D1 dopamine receptor binding
GO:0032268 regulation of cellular protein metabolic process
GO:0032456 endocytic recycling
GO:0036010 protein localization to endosome
GO:0042147 retrograde transport, endosome to Golgi
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:0045056 transcytosis
GO:0050728 negative regulation of inflammatory response
GO:0060161 positive regulation of dopamine receptor signaling pathway
GO:0060548 negative regulation of cell death
GO:0070062 extracellular exosome
GO:0090141 positive regulation of mitochondrial fission
GO:0097422 tubular endosome
GO:0099073 mitochondrion-derived vesicle
GO:0099074 mitochondrion to lysosome transport
GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane
GO:1901215 negative regulation of neuron death
GO:1902823 negative regulation of late endosome to lysosome transport
GO:1902950 regulation of dendritic spine maintenance
GO:1903364 positive regulation of cellular protein catabolic process
GO:1905606 regulation of presynapse assembly
GO:2000331 regulation of terminal button organization

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
VPS35Vps29DIP, UniProt15965486 20923837 details
VPS35Vps35UniProt20923837 details
VPS35Xpo7IntAct29748336 unassigned1673 details