Entity Details

Primary name PRKCA
Entity type gene
Source Source Link

Details

PrimaryID5578
RefseqGeneNG_012206
SymbolPRKCA
Nameprotein kinase C alpha
Chromosome17
Location17q24.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-05-16
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsKPCA_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002159 desmosome assembly
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005178 integrin binding
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0007077 mitotic nuclear membrane disassembly
GO:0007155 cell adhesion
GO:0007411 axon guidance
GO:0008270 zinc ion binding
GO:0010595 positive regulation of endothelial cell migration
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019899 enzyme binding
GO:0030168 platelet activation
GO:0030335 positive regulation of cell migration
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0031966 mitochondrial membrane
GO:0034351 negative regulation of glial cell apoptotic process
GO:0035403 histone kinase activity (H3-T6 specific)
GO:0035408 histone H3-T6 phosphorylation
GO:0035556 intracellular signal transduction
GO:0035866 alphav-beta3 integrin-PKCalpha complex
GO:0038128 ERBB2 signaling pathway
GO:0043488 regulation of mRNA stability
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045651 positive regulation of macrophage differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045780 positive regulation of bone resorption
GO:0045785 positive regulation of cell adhesion
GO:0045931 positive regulation of mitotic cell cycle
GO:0048471 perinuclear region of cytoplasm
GO:0050796 regulation of insulin secretion
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0090330 regulation of platelet aggregation
GO:0097190 apoptotic signaling pathway
GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000707 positive regulation of dense core granule biogenesis

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
PRKCAJak2MINT17290288 details
PRKCAMarcksBioGRID7588787 details
PRKCABcas2BioGRID, IntAct26496610 details
PRKCACtnnbl1BioGRID, IntAct26496610 details