Entity Details

Primary name PRKCI
Entity type gene
Source Source Link

Details

PrimaryID5584
RefseqGene
SymbolPRKCI
Nameprotein kinase C iota
Chromosome3
Location3q26.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsKPCI_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005524 ATP binding
GO:0005543 phospholipid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005923 bicellular tight junction
GO:0006468 protein phosphorylation
GO:0006612 protein targeting to membrane
GO:0007010 cytoskeleton organization
GO:0007015 actin filament organization
GO:0010976 positive regulation of neuron projection development
GO:0015630 microtubule cytoskeleton
GO:0016192 vesicle-mediated transport
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0018105 peptidyl-serine phosphorylation
GO:0031252 cell leading edge
GO:0032869 cellular response to insulin stimulus
GO:0034351 negative regulation of glial cell apoptotic process
GO:0035089 establishment of apical/basal cell polarity
GO:0035556 intracellular signal transduction
GO:0042462 eye photoreceptor cell development
GO:0043066 negative regulation of apoptotic process
GO:0043220 Schmidt-Lanterman incisure
GO:0043524 negative regulation of neuron apoptotic process
GO:0045171 intercellular bridge
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0045216 cell-cell junction organization
GO:0045747 positive regulation of Notch signaling pathway
GO:0046326 positive regulation of glucose import
GO:0046872 metal ion binding
GO:0046903 secretion
GO:0048194 Golgi vesicle budding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060252 positive regulation of glial cell proliferation
GO:0061024 membrane organization
GO:0070062 extracellular exosome
GO:0070555 response to interleukin-1
GO:0070830 bicellular tight junction assembly
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903078 positive regulation of protein localization to plasma membrane
GO:2000353 positive regulation of endothelial cell apoptotic process

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
PRKCIFrs2BioGRID10383403 details
PRKCIDido1BioGRID28330622 details
PRKCICbll1MINT22252131 details
PRKCIPard6bBioGRID, IntAct26496610 details
PRKCIXpo1IntAct26673895 details