Entity Details

Primary name MAPK1
Entity type gene
Source Source Link

Details

PrimaryID5594
RefseqGeneNG_023054
SymbolMAPK1
Namemitogen-activated protein kinase 1
Chromosome22
Location22q11.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-08
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMK01_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000186 obsolete activation of MAPKK activity
GO:0000187 obsolete activation of MAPK activity
GO:0001784 phosphotyrosine residue binding
GO:0003690 double-stranded DNA binding
GO:0004674 protein serine/threonine kinase activity
GO:0004707 MAP kinase activity
GO:0004708 MAP kinase kinase activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005788 endoplasmic reticulum lumen
GO:0005794 Golgi apparatus
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0005925 focal adhesion
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0006935 chemotaxis
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007411 axon guidance
GO:0007568 aging
GO:0007611 learning or memory
GO:0008134 transcription factor binding
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009636 response to toxic substance
GO:0010628 positive regulation of gene expression
GO:0010759 positive regulation of macrophage chemotaxis
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling
GO:0014069 postsynaptic density
GO:0015966 diadenosine tetraphosphate biosynthetic process
GO:0016032 viral process
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019233 sensory perception of pain
GO:0019858 cytosine metabolic process
GO:0019902 phosphatase binding
GO:0030168 platelet activation
GO:0030278 regulation of ossification
GO:0030424 axon
GO:0030641 regulation of cellular pH
GO:0030878 thyroid gland development
GO:0031143 pseudopodium
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0031647 regulation of protein stability
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032839 dendrite cytoplasm
GO:0032872 regulation of stress-activated MAPK cascade
GO:0032991 protein-containing complex
GO:0033598 mammary gland epithelial cell proliferation
GO:0033668 negative regulation by symbiont of host apoptotic process
GO:0034198 cellular response to amino acid starvation
GO:0034614 cellular response to reactive oxygen species
GO:0035094 response to nicotine
GO:0035556 intracellular signal transduction
GO:0035578 azurophil granule lumen
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0038127 ERBB signaling pathway
GO:0042307 positive regulation of protein import into nucleus
GO:0042473 outer ear morphogenesis
GO:0042802 identical protein binding
GO:0043204 perikaryon
GO:0043312 neutrophil degranulation
GO:0043330 response to exogenous dsRNA
GO:0043627 response to estrogen
GO:0045596 negative regulation of cell differentiation
GO:0045727 positive regulation of translation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046697 decidualization
GO:0048538 thymus development
GO:0050852 T cell receptor signaling pathway
GO:0050853 B cell receptor signaling pathway
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0051403 stress-activated MAPK cascade
GO:0051493 regulation of cytoskeleton organization
GO:0051973 positive regulation of telomerase activity
GO:0060020 Bergmann glial cell differentiation
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060291 long-term synaptic potentiation
GO:0060324 face development
GO:0060425 lung morphogenesis
GO:0060440 trachea formation
GO:0060716 labyrinthine layer blood vessel development
GO:0061308 cardiac neural crest cell development involved in heart development
GO:0070371 ERK1 and ERK2 cascade
GO:0070849 response to epidermal growth factor
GO:0071276 cellular response to cadmium ion
GO:0071356 cellular response to tumor necrosis factor
GO:0072584 caveolin-mediated endocytosis
GO:0072686 mitotic spindle
GO:0090170 regulation of Golgi inheritance
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120041 positive regulation of macrophage proliferation
GO:1900034 regulation of cellular response to heat
GO:1903351 cellular response to dopamine
GO:1904355 positive regulation of telomere capping
GO:1904813 ficolin-1-rich granule lumen
GO:2000641 regulation of early endosome to late endosome transport

Diseases

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Interactions

9 interactions