Entity Details

Primary name MAP2K2
Entity type gene
Source Source Link

Details

PrimaryID5605
RefseqGeneNG_007996
SymbolMAP2K2
Namemitogen-activated protein kinase kinase 2
Chromosome19
Location19p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-14
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMP2K2_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000186 obsolete activation of MAPKK activity
GO:0000187 obsolete activation of MAPK activity
GO:0004708 MAP kinase kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005078 MAP-kinase scaffold activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005778 peroxisomal membrane
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0009898 cytoplasmic side of plasma membrane
GO:0010629 negative regulation of gene expression
GO:0030165 PDZ domain binding
GO:0032872 regulation of stress-activated MAPK cascade
GO:0036289 peptidyl-serine autophosphorylation
GO:0043539 protein serine/threonine kinase activator activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0070371 ERK1 and ERK2 cascade
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0090170 regulation of Golgi inheritance
GO:0097110 scaffold protein binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA
GO:2000641 regulation of early endosome to late endosome transport

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
MAP2K2Ksr1BioGRID, MINT10409742 26549023 details
MAP2K2FlnaBioGRID9006895 details
MAP2K2Xpo1IntAct26673895 details