Entity Details

Primary name MAP2K5
Entity type gene
Source Source Link

Details

PrimaryID5607
RefseqGeneNG_029143
SymbolMAP2K5
Namemitogen-activated protein kinase kinase 5
Chromosome15
Location15q23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-14
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMP2K5_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000187 obsolete activation of MAPK activity
GO:0004672 protein kinase activity
GO:0004708 MAP kinase kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005819 spindle
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0007507 heart development
GO:0030307 positive regulation of cell growth
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032717 negative regulation of interleukin-8 production
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051247 positive regulation of protein metabolic process
GO:0060761 negative regulation of response to cytokine stimulus
GO:0070375 ERK5 cascade
GO:0071363 cellular response to growth factor stimulus
GO:0071499 cellular response to laminar fluid shear stress
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MAP2K5Map3k3BioGRID10593883 details