Entity Details

Primary name PARD3
Entity type gene
Source Source Link

Details

PrimaryID56288
RefseqGeneNG_052602
SymbolPARD3
Namepar-3 family cell polarity regulator
Chromosome10
Location10p11.22-p11.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPARD3_HUMAN

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0005938 cell cortex
GO:0006612 protein targeting to membrane
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007409 axonogenesis
GO:0008104 protein localization
GO:0008356 asymmetric cell division
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0012505 endomembrane system
GO:0016324 apical plasma membrane
GO:0019903 protein phosphatase binding
GO:0022011 myelination in peripheral nervous system
GO:0030010 establishment of cell polarity
GO:0030054 cell junction
GO:0031643 positive regulation of myelination
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0032991 protein-containing complex
GO:0033269 internode region of axon
GO:0035091 phosphatidylinositol binding
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043296 apical junction complex
GO:0044295 axonal growth cone
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0051660 establishment of centrosome localization
GO:0060341 regulation of cellular localization
GO:0065003 protein-containing complex assembly
GO:0070830 bicellular tight junction assembly
GO:0090162 establishment of epithelial cell polarity

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
PARD3Tiam2MINT19893486 details
PARD3PrkciBioGRID, DIP, IntAct22579248 26496610 details
PARD3Pard6bBioGRID, IntAct10934474 26496610 details
PARD3Cdc42IntAct10934474 details
PARD3Lats2IntAct24255178 details
PARD3Ppp1cbBioGRID, IntAct26496610 details
PARD3Cdc23BioGRID, IntAct26496610 details
PARD3Cdc26BioGRID, IntAct26496610 details
PARD3Yap1BioGRID, IntAct26496610 details