Entity Details

Primary name TSC1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9EP53
EntryNameTSC1_MOUSE
FullNameHamartin
TaxID10090
Evidenceevidence at protein level
Length1161
SequenceStatuscomplete
DateCreated2009-07-28
DateModified2021-06-02

Ontological Relatives

GenesTsc1

GO terms

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GOName
GO:0001822 kidney development
GO:0001843 neural tube closure
GO:0001952 regulation of cell-matrix adhesion
GO:0002250 adaptive immune response
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005938 cell cortex
GO:0006407 rRNA export from nucleus
GO:0006417 regulation of translation
GO:0006813 potassium ion transport
GO:0007160 cell-matrix adhesion
GO:0007399 nervous system development
GO:0008285 negative regulation of cell population proliferation
GO:0008344 adult locomotory behavior
GO:0010977 negative regulation of neuron projection development
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016239 positive regulation of macroautophagy
GO:0016242 negative regulation of macroautophagy
GO:0017148 negative regulation of translation
GO:0021766 hippocampus development
GO:0021987 cerebral cortex development
GO:0030027 lamellipodium
GO:0030030 cell projection organization
GO:0030426 growth cone
GO:0030544 Hsp70 protein binding
GO:0032007 negative regulation of TOR signaling
GO:0032780 negative regulation of ATPase activity
GO:0032794 GTPase activating protein binding
GO:0032868 response to insulin
GO:0032991 protein-containing complex
GO:0033596 TSC1-TSC2 complex
GO:0034260 negative regulation of GTPase activity
GO:0042030 ATPase inhibitor activity
GO:0042552 myelination
GO:0042995 cell projection
GO:0043231 intracellular membrane-bounded organelle
GO:0043379 memory T cell differentiation
GO:0043666 regulation of phosphoprotein phosphatase activity
GO:0044877 protein-containing complex binding
GO:0045792 negative regulation of cell size
GO:0045859 regulation of protein kinase activity
GO:0046323 glucose import
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0047485 protein N-terminus binding
GO:0048471 perinuclear region of cytoplasm
GO:0050808 synapse organization
GO:0050821 protein stabilization
GO:0051087 chaperone binding
GO:0051492 regulation of stress fiber assembly
GO:0051496 positive regulation of stress fiber assembly
GO:0051726 regulation of cell cycle
GO:0051879 Hsp90 protein binding
GO:0051893 regulation of focal adhesion assembly
GO:0051894 positive regulation of focal adhesion assembly
GO:0055007 cardiac muscle cell differentiation
GO:0090630 activation of GTPase activity
GO:0090650 cellular response to oxygen-glucose deprivation
GO:0101031 chaperone complex
GO:1901214 regulation of neuron death
GO:1903204 negative regulation of oxidative stress-induced neuron death

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR007483 HamartinFamilyFamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily

Diseases

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