Entity Details

Primary name PTK2
Entity type gene
Source Source Link

Details

PrimaryID5747
RefseqGeneNG_029467
SymbolPTK2
Nameprotein tyrosine kinase 2
Chromosome8
Location8q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsFAK1_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001525 angiogenesis
GO:0001725 stress fiber
GO:0001890 placenta development
GO:0001932 regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0003007 heart morphogenesis
GO:0003779 actin binding
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005178 integrin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007172 signal complex assembly
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007411 axon guidance
GO:0008284 positive regulation of cell population proliferation
GO:0008360 regulation of cell shape
GO:0008432 JUN kinase binding
GO:0010594 regulation of endothelial cell migration
GO:0010632 regulation of epithelial cell migration
GO:0010759 positive regulation of macrophage chemotaxis
GO:0010763 positive regulation of fibroblast migration
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0022408 negative regulation of cell-cell adhesion
GO:0030010 establishment of cell polarity
GO:0030154 cell differentiation
GO:0030155 regulation of cell adhesion
GO:0030335 positive regulation of cell migration
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0033628 regulation of cell adhesion mediated by integrin
GO:0035995 detection of muscle stretch
GO:0036064 ciliary basal body
GO:0038007 netrin-activated signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042127 regulation of cell population proliferation
GO:0042169 SH2 domain binding
GO:0043066 negative regulation of apoptotic process
GO:0043087 regulation of GTPase activity
GO:0043197 dendritic spine
GO:0043231 intracellular membrane-bounded organelle
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 innate immune response
GO:0045667 regulation of osteoblast differentiation
GO:0045860 positive regulation of protein kinase activity
GO:0046777 protein autophosphorylation
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048013 ephrin receptor signaling pathway
GO:0048870 cell motility
GO:0051493 regulation of cytoskeleton organization
GO:0051893 regulation of focal adhesion assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0060396 growth hormone receptor signaling pathway
GO:0090303 positive regulation of wound healing
GO:0120041 positive regulation of macrophage proliferation
GO:1900024 regulation of substrate adhesion-dependent cell spreading
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process
GO:2000811 negative regulation of anoikis

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
PTK2SrcMINT18560762 21266176 details
PTK2Elavl1MINT18273060 details
PTK2Tgfb1i1BioGRID, UniProt9756887 details
PTK2Dctn5BioGRID, IntAct26496610 details