Entity Details

Primary name RENT1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9EPU0
EntryNameRENT1_MOUSE
FullNameRegulator of nonsense transcripts 1
TaxID10090
Evidenceevidence at protein level
Length1124
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesUpf1

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0000932 P-body
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006449 regulation of translational termination
GO:0008270 zinc ion binding
GO:0009048 dosage compensation by inactivation of X chromosome
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032204 regulation of telomere maintenance
GO:0035145 exon-exon junction complex
GO:0042162 telomeric DNA binding
GO:0044530 supraspliceosomal complex
GO:0044770 cell cycle phase transition
GO:0048471 perinuclear region of cytoplasm
GO:0061014 positive regulation of mRNA catabolic process
GO:0061158 3'-UTR-mediated mRNA destabilization
GO:0071044 histone mRNA catabolic process
GO:0071222 cellular response to lipopolysaccharide
GO:0071347 cellular response to interleukin-1

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR006935 Helicase/UvrB, N-terminalDomainDomain
IPR018999 RNA helicase UPF1, Cys/His rich zinc-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR040812 RNA helicase UPF1, 1B domainDomainDomain
IPR041677 DNA2/NAM7 helicase, helicase domainDomainDomain
IPR041679 DNA2/NAM7 helicase-like, C-terminalDomainDomain

Diseases

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Interactions

4 interactions