Entity Details

Primary name PREX1
Entity type gene
Source Source Link

Details

PrimaryID57580
RefseqGene
SymbolPREX1
Namephosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
Chromosome20
Location20q13.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPREX1_HUMAN

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005543 phospholipid binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006801 superoxide metabolic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0019899 enzyme binding
GO:0030041 actin filament polymerization
GO:0030217 T cell differentiation
GO:0030335 positive regulation of cell migration
GO:0030426 growth cone
GO:0030593 neutrophil chemotaxis
GO:0030833 regulation of actin filament polymerization
GO:0035556 intracellular signal transduction
GO:0042119 neutrophil activation
GO:0043065 positive regulation of apoptotic process
GO:0043198 dendritic shaft
GO:0048471 perinuclear region of cytoplasm
GO:0050773 regulation of dendrite development
GO:0051056 regulation of small GTPase mediated signal transduction
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PREX1Akt1I2D21339740 details
PREX1Akt2I2D21339740 details
PREX1Arhgap18BioGRID, IntAct32203420 details