Entity Details

Primary name CHD8
Entity type gene
Source Source Link

Details

PrimaryID57680
RefseqGeneNG_021249
SymbolCHD8
Namechromodomain helicase DNA binding protein 8
Chromosome14
Location14q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCHD8_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001701 in utero embryonic development
GO:0002039 p53 binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007420 brain development
GO:0008013 beta-catenin binding
GO:0008094 ATPase, acting on DNA
GO:0016055 Wnt signaling pathway
GO:0032991 protein-containing complex
GO:0035064 methylated histone binding
GO:0035176 social behavior
GO:0042393 histone binding
GO:0043044 ATP-dependent chromatin remodeling
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045945 positive regulation of transcription by RNA polymerase III
GO:0048565 digestive tract development
GO:0060134 prepulse inhibition
GO:0070016 armadillo repeat domain binding
GO:0070615 nucleosome-dependent ATPase activity
GO:0071339 MLL1 complex
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:2000270 negative regulation of fibroblast apoptotic process

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CHD8Snap29BioGRID, IntAct26496610 details
CHD8Gtf2bBioGRID, IntAct26496610 details