Entity Details

Primary name TBX18_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9EPZ6
EntryNameTBX18_MOUSE
FullNameT-box transcription factor TBX18
TaxID10090
Evidenceevidence at protein level
Length613
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesTbx18

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001708 cell fate specification
GO:0001756 somitogenesis
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0003163 sinoatrial node development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007605 sensory perception of sound
GO:0009948 anterior/posterior axis specification
GO:0016331 morphogenesis of embryonic epithelium
GO:0022409 positive regulation of cell-cell adhesion
GO:0030154 cell differentiation
GO:0042803 protein homodimerization activity
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051145 smooth muscle cell differentiation
GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0060930 sinoatrial node cell fate commitment
GO:0060931 sinoatrial node cell development
GO:0072189 ureter development
GO:0090103 cochlea morphogenesis
GO:0090571 RNA polymerase II transcription repressor complex
GO:0098907 regulation of SA node cell action potential
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TBX18_MOUSETLX3_MOUSEBioGRID, IntAct20211142 details