Entity Details

Primary name RAF1
Entity type gene
Source Source Link

Details

PrimaryID5894
RefseqGeneNG_007467
SymbolRAF1
NameRaf-1 proto-oncogene, serine/threonine kinase
Chromosome3
Location3p25.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-03-30
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsRAF1_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000186 obsolete activation of MAPKK activity
GO:0001666 response to hypoxia
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002250 adaptive immune response
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0007190 activation of adenylate cyclase activity
GO:0007507 heart development
GO:0008179 adenylate cyclase binding
GO:0008285 negative regulation of cell population proliferation
GO:0010856 adenylate cyclase activator activity
GO:0016607 nuclear speck
GO:0019899 enzyme binding
GO:0030154 cell differentiation
GO:0030168 platelet activation
GO:0030878 thyroid gland development
GO:0031143 pseudopodium
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034220 ion transmembrane transport
GO:0035019 somatic stem cell population maintenance
GO:0035023 regulation of Rho protein signal transduction
GO:0035773 insulin secretion involved in cellular response to glucose stimulus
GO:0035994 response to muscle stretch
GO:0042060 wound healing
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044877 protein-containing complex binding
GO:0045104 intermediate filament cytoskeleton organization
GO:0045595 regulation of cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048538 thymus development
GO:0060324 face development
GO:0071550 death-inducing signaling complex assembly
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000145 regulation of cell motility

Diseases

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