Entity Details

Primary name UPF1
Entity type gene
Source Source Link

Details

PrimaryID5976
RefseqGene
SymbolUPF1
NameUPF1 RNA helicase and ATPase
Chromosome19
Location19p13.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsRENT1_HUMAN

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0000932 P-body
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006406 mRNA export from nucleus
GO:0006449 regulation of translational termination
GO:0008270 zinc ion binding
GO:0009048 dosage compensation by inactivation of X chromosome
GO:0016032 viral process
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032204 regulation of telomere maintenance
GO:0035145 exon-exon junction complex
GO:0042162 telomeric DNA binding
GO:0044530 supraspliceosomal complex
GO:0044770 cell cycle phase transition
GO:0061014 positive regulation of mRNA catabolic process
GO:0061158 3'-UTR-mediated mRNA destabilization
GO:0071044 histone mRNA catabolic process
GO:0071222 cellular response to lipopolysaccharide
GO:0071347 cellular response to interleukin-1

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
UPF1Gspt2UniProt16452507 details
UPF1Rc3h1IntAct23663784 details
UPF1Rc3h2IntAct23663784 details
UPF1Taok2BioGRID, IntAct26496610 details
UPF1Elavl1BioGRID, IntAct26496610 details
UPF1Sumo3BioGRID, IntAct26496610 details
UPF1Xpo1IntAct26673895 details
UPF1MecomMINT30462309 details