Entity Details

Primary name RFC1
Entity type gene
Source Source Link

Details

PrimaryID5981
RefseqGene
SymbolRFC1
Namereplication factor C subunit 1
Chromosome4
Location4p14
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsRFC1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005663 DNA replication factor C complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006261 DNA-dependent DNA replication
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006287 base-excision repair, gap-filling
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0007004 telomere maintenance via telomerase
GO:0008047 enzyme activator activity
GO:0019904 protein domain specific binding
GO:0019985 translesion synthesis
GO:0031391 Elg1 RFC-like complex
GO:0032201 telomere maintenance via semi-conservative replication
GO:0033683 nucleotide-excision repair, DNA incision
GO:0042276 error-prone translesion synthesis
GO:0042769 DNA damage response, detection of DNA damage
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0061860 DNA clamp unloader activity
GO:0070062 extracellular exosome
GO:0070987 error-free translesion synthesis
GO:0090618 DNA clamp unloading

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
RFC1Sap25IntAct16449650 details
RFC1Rpl35BioGRID, IntAct26496610 details
RFC1PcnaBioGRID, IntAct26496610 details
RFC1Kctd5BioGRID, IntAct26496610 details
RFC1Brwd3BioGRID, IntAct26496610 details
RFC1Rrbp1BioGRID, IntAct26496610 details
RFC1Eif3iBioGRID, IntAct26496610 details
RFC1Prdm16MINT30462309 details
RFC1MecomMINT30462309 details