Entity Details

Primary name TRIM27
Entity type gene
Source Source Link

Details

PrimaryID5987
RefseqGene
SymbolTRIM27
Nametripartite motif containing 27
Chromosome6
Location6p22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsTRI27_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000209 protein polyubiquitination
GO:0001650 fibrillar center
GO:0002820 negative regulation of adaptive immune response
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005829 cytosol
GO:0006469 negative regulation of protein kinase activity
GO:0007283 spermatogenesis
GO:0008270 zinc ion binding
GO:0010468 regulation of gene expression
GO:0010508 positive regulation of autophagy
GO:0016567 protein ubiquitination
GO:0016605 PML body
GO:0019901 protein kinase binding
GO:0031965 nuclear membrane
GO:0032703 negative regulation of interleukin-2 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032729 positive regulation of interferon-gamma production
GO:0032880 regulation of protein localization
GO:0032897 negative regulation of viral transcription
GO:0033668 negative regulation by symbiont of host apoptotic process
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0042147 retrograde transport, endosome to Golgi
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0045814 negative regulation of gene expression, epigenetic
GO:0046596 regulation of viral entry into host cell
GO:0046872 metal ion binding
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0061630 ubiquitin protein ligase activity
GO:0070534 protein K63-linked ubiquitination
GO:0090281 negative regulation of calcium ion import

Diseases

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Interactions

13 interactions

InteractorPartnerSourcesPublicationsLink
TRIM27Lats2IntAct24255178 details
TRIM27Cep135BioGRID, IntAct26496610 details
TRIM27Nedd1BioGRID, IntAct26496610 details
TRIM27Mad2l1BioGRID, IntAct26496610 details
TRIM27Ranbp2BioGRID, IntAct26496610 details
TRIM27Cdc23BioGRID, IntAct26496610 details
TRIM27Cd2apBioGRID, IntAct26496610 details
TRIM27Pcgf1BioGRID, IntAct26496610 details
TRIM27GpkowBioGRID, IntAct26496610 details
TRIM27Tmed2BioGRID, IntAct26496610 details
TRIM27Prkaa1BioGRID, IntAct26496610 details
TRIM27Ring1BioGRID, IntAct26496610 details
TRIM27Prdm16MINT30462309 details