Entity Details

Primary name ERAP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9EQH2
EntryNameERAP1_MOUSE
FullNameEndoplasmic reticulum aminopeptidase 1
TaxID10090
Evidenceevidence at protein level
Length930
SequenceStatuscomplete
DateCreated2002-03-05
DateModified2021-06-02

Ontological Relatives

GenesErap1

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0004177 aminopeptidase activity
GO:0005138 interleukin-6 receptor binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006509 membrane protein ectodomain proteolysis
GO:0007165 signal transduction
GO:0008217 regulation of blood pressure
GO:0008233 peptidase activity
GO:0008235 metalloexopeptidase activity
GO:0008270 zinc ion binding
GO:0016021 integral component of membrane
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0042277 peptide binding
GO:0043171 peptide catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0045766 positive regulation of angiogenesis
GO:0070006 metalloaminopeptidase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolaseFamilyFamily
IPR014782 Peptidase M1, membrane alanine aminopeptidaseDomainDomain
IPR024571 ERAP1-like C-terminal domainDomainDomain
IPR033520 Endoplasmic reticulum aninopeptidase 1FamilyFamily
IPR034016 Aminopeptidase N-typeFamilyFamily
IPR042097 Aminopeptidase N-like , N-terminalFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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