Entity Details

Primary name TPC1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9EQJ0
EntryNameTPC1_MOUSE
FullNameTwo pore calcium channel protein 1
TaxID10090
Evidenceevidence at protein level
Length817
SequenceStatuscomplete
DateCreated2007-02-06
DateModified2021-06-02

Ontological Relatives

GenesTpcn1

GO terms

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GOName
GO:0005245 voltage-gated calcium channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005765 lysosomal membrane
GO:0010008 endosome membrane
GO:0010508 positive regulation of autophagy
GO:0015280 ligand-gated sodium channel activity
GO:0016021 integral component of membrane
GO:0034765 regulation of ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0072345 NAADP-sensitive calcium-release channel activity
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding

Subcellular Location

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Subcellular Location
Endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR005821 Ion transport domainDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028801 Two pore calcium channel protein 1, animalFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TPC1_MOUSETPC1_MOUSEDIP29562233 details