Entity Details

Primary name BCR
Entity type gene
Source Source Link

Details

PrimaryID613
RefseqGeneNG_009244
SymbolBCR
NameBCR activator of RhoGEF and GTPase
Chromosome22
Location22q11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBCR_HUMAN

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0016020 membrane
GO:0019899 enzyme binding
GO:0030216 keratinocyte differentiation
GO:0030424 axon
GO:0032991 protein-containing complex
GO:0035023 regulation of Rho protein signal transduction
GO:0043197 dendritic spine
GO:0046777 protein autophosphorylation
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048041 focal adhesion assembly
GO:0050804 modulation of chemical synaptic transmission
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0070062 extracellular exosome
GO:0090630 activation of GTPase activity
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
BCRNumbBioGRID, IntAct23211419 details
BCRSh2d5IntAct25331951 details
BCRCrkIntAct20697350 details
BCRDok1IntAct20697350 details
BCRDok2IntAct20697350 details
BCRGrb2IntAct20697350 details
BCRScaiBioGRID, IntAct26496610 details
BCRXpo1IntAct26673895 details