Entity Details

Primary name CCL5
Entity type gene
Source Source Link

Details

PrimaryID6352
RefseqGeneNG_015990
SymbolCCL5
NameC-C motif chemokine ligand 5
Chromosome17
Location17q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCCL5_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0002407 dendritic cell chemotaxis
GO:0002548 monocyte chemotaxis
GO:0002676 regulation of chronic inflammatory response
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004672 protein kinase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006887 exocytosis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007159 leukocyte cell-cell adhesion
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0009615 response to virus
GO:0009636 response to toxic substance
GO:0010536 positive regulation of activation of Janus kinase activity
GO:0010759 positive regulation of macrophage chemotaxis
GO:0010820 positive regulation of T cell chemotaxis
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016004 phospholipase activator activity
GO:0019221 cytokine-mediated signaling pathway
GO:0030298 receptor signaling protein tyrosine kinase activator activity
GO:0030335 positive regulation of cell migration
GO:0030593 neutrophil chemotaxis
GO:0031328 positive regulation of cellular biosynthetic process
GO:0031584 activation of phospholipase D activity
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0031726 CCR1 chemokine receptor binding
GO:0031729 CCR4 chemokine receptor binding
GO:0031730 CCR5 chemokine receptor binding
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin
GO:0034112 positive regulation of homotypic cell-cell adhesion
GO:0042056 chemoattractant activity
GO:0042102 positive regulation of T cell proliferation
GO:0042119 neutrophil activation
GO:0042327 positive regulation of phosphorylation
GO:0042379 chemokine receptor binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043491 protein kinase B signaling
GO:0043547 positive regulation of GTPase activity
GO:0043621 protein self-association
GO:0043922 negative regulation by host of viral transcription
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045070 positive regulation of viral genome replication
GO:0045071 negative regulation of viral genome replication
GO:0045089 positive regulation of innate immune response
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0045785 positive regulation of cell adhesion
GO:0045948 positive regulation of translational initiation
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046817 chemokine receptor antagonist activity
GO:0048020 CCR chemokine receptor binding
GO:0048245 eosinophil chemotaxis
GO:0048246 macrophage chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050796 regulation of insulin secretion
GO:0050863 regulation of T cell activation
GO:0051928 positive regulation of calcium ion transport
GO:0070098 chemokine-mediated signaling pathway
GO:0070233 negative regulation of T cell apoptotic process
GO:0070234 positive regulation of T cell apoptotic process
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071407 cellular response to organic cyclic compound
GO:0090026 positive regulation of monocyte chemotaxis
GO:0098586 cellular response to virus
GO:1901214 regulation of neuron death
GO:2000406 positive regulation of T cell migration
GO:2000503 positive regulation of natural killer cell chemotaxis

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CCL5Igfbp7BioGRID12847218 details
CCL5Pf4bhf-ucl28381538 details