Entity Details

Primary name RPGF4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9EQZ6
EntryNameRPGF4_MOUSE
FullNameRap guanine nucleotide exchange factor 4
TaxID10090
Evidenceevidence at protein level
Length1011
SequenceStatuscomplete
DateCreated2003-06-20
DateModified2021-06-02

Ontological Relatives

GenesRapgef4

GO terms

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GOName
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005903 brush border
GO:0005929 cilium
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0014069 postsynaptic density
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0017156 calcium-ion regulated exocytosis
GO:0017157 regulation of exocytosis
GO:0019933 cAMP-mediated signaling
GO:0030073 insulin secretion
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030552 cAMP binding
GO:0031267 small GTPase binding
GO:0032991 protein-containing complex
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0044316 cone cell pedicle
GO:0044877 protein-containing complex binding
GO:0050714 positive regulation of protein secretion
GO:0050773 regulation of dendrite development
GO:0050805 negative regulation of synaptic transmission
GO:0060076 excitatory synapse
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098693 regulation of synaptic vesicle cycle
GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
GO:0098978 glutamatergic synapse
GO:0099175 regulation of postsynapse organization
GO:1904457 positive regulation of neuronal action potential

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000591 DEP domainDomainDomain
IPR000595 Cyclic nucleotide-binding domainDomainDomain
IPR000651 Ras-like guanine nucleotide exchange factor, N-terminalDomainDomain
IPR001895 Ras guanine-nucleotide exchange factors catalytic domainDomainDomain
IPR008937 Ras-like guanine nucleotide exchange factorFamilyFamily
IPR014710 RmlC-like jelly roll foldFamilyHomologous superfamily
IPR018490 Cyclic nucleotide-binding-likeFamilyHomologous superfamily
IPR019804 Ras guanine-nucleotide exchange factor, conserved siteSiteConserved site
IPR023578 Ras guanine nucleotide exchange factor domain superfamilyFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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