Entity Details

Primary name BLM
Entity type gene
Source Source Link

Details

PrimaryID641
RefseqGeneNG_007272
SymbolBLM
NameBLM RecQ like helicase
Chromosome15
Location15q26.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-03
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsBLM_HUMAN

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000228 nuclear chromosome
GO:0000400 four-way junction DNA binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000729 DNA double-strand break processing
GO:0000800 lateral element
GO:0002039 p53 binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 cellular response to DNA damage stimulus
GO:0007095 mitotic G2 DNA damage checkpoint signaling
GO:0008094 ATPase, acting on DNA
GO:0008270 zinc ion binding
GO:0009378 four-way junction helicase activity
GO:0010165 response to X-ray
GO:0016363 nuclear matrix
GO:0016605 PML body
GO:0016887 ATP hydrolysis activity
GO:0031297 replication fork processing
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032508 DNA duplex unwinding
GO:0032991 protein-containing complex
GO:0036310 ATP-dependent DNA/DNA annealing activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0044806 G-quadruplex DNA unwinding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045910 negative regulation of DNA recombination
GO:0048478 replication fork protection
GO:0051259 protein complex oligomerization
GO:0051260 protein homooligomerization
GO:0051782 negative regulation of cell division
GO:0051880 G-quadruplex DNA binding
GO:0061749 forked DNA-dependent helicase activity
GO:0061820 telomeric D-loop disassembly
GO:0061821 telomeric D-loop binding
GO:0061849 telomeric G-quadruplex DNA binding
GO:0071479 cellular response to ionizing radiation
GO:0072711 cellular response to hydroxyurea
GO:0072757 cellular response to camptothecin
GO:0090329 regulation of DNA-dependent DNA replication
GO:0090656 t-circle formation
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
BLMTop3aBioGRID, IntAct20360068 details
BLMRmi1BioGRID, IntAct20360068 details
BLMErcc6lBioGRID, IntAct20360068 details
BLMRpl35BioGRID, IntAct26496610 details
BLMEif3eBioGRID, IntAct26496610 details
BLMPaxip1UniProt17500065 details