Entity Details

Primary name SHC1
Entity type gene
Source Source Link

Details

PrimaryID6464
RefseqGeneNG_029028
SymbolSHC1
NameSHC adaptor protein 1
Chromosome1
Location1q21.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-09-09
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsSHC1_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000187 obsolete activation of MAPK activity
GO:0001525 angiogenesis
GO:0001784 phosphotyrosine residue binding
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005158 insulin receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005168 neurotrophin TRKA receptor binding
GO:0005543 phospholipid binding
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007176 regulation of epidermal growth factor-activated receptor activity
GO:0007265 Ras protein signal transduction
GO:0007411 axon guidance
GO:0007507 heart development
GO:0008284 positive regulation of cell population proliferation
GO:0008286 insulin receptor signaling pathway
GO:0016032 viral process
GO:0016525 negative regulation of angiogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0030971 receptor tyrosine kinase binding
GO:0031532 actin cytoskeleton reorganization
GO:0035723 interleukin-15-mediated signaling pathway
GO:0036498 IRE1-mediated unfolded protein response
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038110 interleukin-2-mediated signaling pathway
GO:0038128 ERBB2 signaling pathway
GO:0040008 regulation of growth
GO:0042742 defense response to bacterium
GO:0043066 negative regulation of apoptotic process
GO:0043410 positive regulation of MAPK cascade
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046875 ephrin receptor binding
GO:0048408 epidermal growth factor binding
GO:0050900 leukocyte migration
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070435 Shc-EGFR complex
GO:0071363 cellular response to growth factor stimulus
GO:0071864 positive regulation of cell proliferation in bone marrow
GO:0090322 regulation of superoxide metabolic process
GO:0098609 cell-cell adhesion

Diseases

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