Entity Details

Primary name SMURF2
Entity type gene
Source Source Link

Details

PrimaryID64750
RefseqGene
SymbolSMURF2
NameSMAD specific E3 ubiquitin protein ligase 2
Chromosome17
Location17q23.3-q24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-01-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSMUF2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005160 transforming growth factor beta receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination
GO:0016579 protein deubiquitination
GO:0016607 nuclear speck
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0030579 ubiquitin-dependent SMAD protein catabolic process
GO:0042802 identical protein binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045121 membrane raft
GO:0045732 positive regulation of protein catabolic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046332 SMAD binding
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061630 ubiquitin protein ligase activity
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901165 positive regulation of trophoblast cell migration

Diseases

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