Entity Details

Primary name SIAH1
Entity type gene
Source Source Link

Details

PrimaryID6477
RefseqGeneNG_029599
SymbolSIAH1
Namesiah E3 ubiquitin protein ligase 1
Chromosome16
Location16q12.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-05-15
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSIAH1_HUMAN

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006915 apoptotic process
GO:0007049 cell cycle
GO:0007283 spermatogenesis
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0008022 protein C-terminus binding
GO:0008270 zinc ion binding
GO:0009653 anatomical structure morphogenesis
GO:0030163 protein catabolic process
GO:0030877 beta-catenin destruction complex
GO:0031624 ubiquitin conjugating enzyme binding
GO:0031648 protein destabilization
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051402 neuron apoptotic process
GO:0061630 ubiquitin protein ligase activity
GO:1902842 negative regulation of netrin-activated signaling pathway
GO:1990000 amyloid fibril formation
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

6 interactions