Entity Details

Primary name SIAH2
Entity type gene
Source Source Link

Details

PrimaryID6478
RefseqGene
SymbolSIAH2
Namesiah E3 ubiquitin protein ligase 2
Chromosome3
Location3q25.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-12-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSIAH2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000209 protein polyubiquitination
GO:0003714 transcription corepressor activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006915 apoptotic process
GO:0007049 cell cycle
GO:0007264 small GTPase mediated signal transduction
GO:0007275 multicellular organism development
GO:0008270 zinc ion binding
GO:0016579 protein deubiquitination
GO:0031396 regulation of protein ubiquitination
GO:0031624 ubiquitin conjugating enzyme binding
GO:0042752 regulation of circadian rhythm
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0044257 cellular protein catabolic process
GO:0048511 rhythmic process
GO:0061630 ubiquitin protein ligase activity
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1902842 negative regulation of netrin-activated signaling pathway
GO:1990000 amyloid fibril formation
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Diseases

Show/Hide Table

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SIAH2Pou2af1IntAct11483518 details
SIAH2Akap1BioGRID18323779 details
SIAH2Oprd1IntAct23840749 details