Entity Details

Primary name GCYA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ERL9
EntryNameGCYA1_MOUSE
FullNameGuanylate cyclase soluble subunit alpha-1
TaxID10090
Evidenceevidence at protein level
Length691
SequenceStatuscomplete
DateCreated2003-01-17
DateModified2021-06-02

Ontological Relatives

GenesGucy1a1

GO terms

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GOName
GO:0004383 guanylate cyclase activity
GO:0005525 GTP binding
GO:0006182 cGMP biosynthetic process
GO:0008074 guanylate cyclase complex, soluble
GO:0008217 regulation of blood pressure
GO:0010750 positive regulation of nitric oxide mediated signal transduction
GO:0020037 heme binding
GO:0032991 protein-containing complex
GO:0035556 intracellular signal transduction
GO:0043167 ion binding
GO:0044877 protein-containing complex binding
GO:0060087 relaxation of vascular associated smooth muscle
GO:0098925 retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclaseDomainDomain
IPR011645 Haem NO binding associatedDomainDomain
IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved siteSiteConserved site
IPR024096 NO signalling/Golgi transport ligand-binding domain superfamilyFamilyHomologous superfamily
IPR029787 Nucleotide cyclaseFamilyHomologous superfamily
IPR038158 H-NOX domain superfamilyFamilyHomologous superfamily
IPR042463 Haem NO binding associated domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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