Entity Details

Primary name SOS1
Entity type gene
Source Source Link

Details

PrimaryID6654
RefseqGeneNG_007530
SymbolSOS1
NameSOS Ras/Rac guanine nucleotide exchange factor 1
Chromosome2
Location2p22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSOS1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000165 MAPK cascade
GO:0001782 B cell homeostasis
GO:0001942 hair follicle development
GO:0003209 cardiac atrium morphogenesis
GO:0003344 pericardium morphogenesis
GO:0003677 DNA binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007265 Ras protein signal transduction
GO:0007296 vitellogenesis
GO:0007411 axon guidance
GO:0008286 insulin receptor signaling pathway
GO:0014069 postsynaptic density
GO:0017124 SH3 domain binding
GO:0019221 cytokine-mediated signaling pathway
GO:0033081 regulation of T cell differentiation in thymus
GO:0035264 multicellular organism growth
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038128 ERBB2 signaling pathway
GO:0042129 regulation of T cell proliferation
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0046982 protein heterodimerization activity
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048514 blood vessel morphogenesis
GO:0050900 leukocyte migration
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0060021 roof of mouth development
GO:0061029 eyelid development in camera-type eye
GO:0061384 heart trabecula morphogenesis
GO:1904693 midbrain morphogenesis
GO:2000973 regulation of pro-B cell differentiation

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
SOS1Grap2BioGRID9872323 details
SOS1Bin1BioGRID9182529 details
SOS1Itsn1MINT15824104 details
SOS1Arhgap18BioGRID, IntAct32203420 details