Entity Details

Primary name SPG7
Entity type gene
Source Source Link

Details

PrimaryID6687
RefseqGeneNG_008082
SymbolSPG7
NameSPG7 matrix AAA peptidase subunit, paraplegin
Chromosome16
Location16q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-06-25
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsSPG7_HUMAN

GO terms

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GOName
GO:0004176 ATP-dependent peptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005757 mitochondrial permeability transition pore complex
GO:0006508 proteolysis
GO:0006851 mitochondrial calcium ion transmembrane transport
GO:0007399 nervous system development
GO:0008053 mitochondrial fusion
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
GO:0034982 mitochondrial protein processing
GO:0042407 cristae formation
GO:0046902 regulation of mitochondrial membrane permeability
GO:0051082 unfolded protein binding
GO:0065003 protein-containing complex assembly
GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
SPG7Flot1BioGRID, IntAct26496610 details
SPG7KifbpBioGRID, IntAct26496610 details
SPG7Tpx2BioGRID, IntAct26496610 details
SPG7Ndc80BioGRID, IntAct26496610 details
SPG7JunbBioGRID, IntAct26496610 details
SPG7Ring1BioGRID, IntAct26496610 details