Entity Details

Primary name TRIM21
Entity type gene
Source Source Link

Details

PrimaryID6737
RefseqGene
SymbolTRIM21
Nametripartite motif containing 21
Chromosome11
Location11p15.4
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-10-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsRO52_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000209 protein polyubiquitination
GO:0000932 P-body
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0003723 RNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005776 autophagosome
GO:0005829 cytosol
GO:0006513 protein monoubiquitination
GO:0007049 cell cycle
GO:0008270 zinc ion binding
GO:0010468 regulation of gene expression
GO:0010508 positive regulation of autophagy
GO:0016567 protein ubiquitination
GO:0019901 protein kinase binding
GO:0031410 cytoplasmic vesicle
GO:0031648 protein destabilization
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032092 positive regulation of protein binding
GO:0032479 regulation of type I interferon production
GO:0032880 regulation of protein localization
GO:0032897 negative regulation of viral transcription
GO:0034341 response to interferon-gamma
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0045787 positive regulation of cell cycle
GO:0045824 negative regulation of innate immune response
GO:0046596 regulation of viral entry into host cell
GO:0046598 positive regulation of viral entry into host cell
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051865 protein autoubiquitination
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0061630 ubiquitin protein ligase activity
GO:0070534 protein K63-linked ubiquitination
GO:0090086 negative regulation of protein deubiquitination
GO:1902187 negative regulation of viral release from host cell
GO:1990904 ribonucleoprotein complex

Diseases

Show/Hide Table

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
TRIM21CskBioGRID, IntAct26496610 details
TRIM21JunbBioGRID, IntAct26496610 details
TRIM21Prdm16MINT30462309 details
TRIM21MecomMINT30462309 details
TRIM21Mdm2BioGRID24980433 details