Entity Details

Primary name ARHG7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ES28
EntryNameARHG7_MOUSE
FullNameRho guanine nucleotide exchange factor 7
TaxID10090
Evidenceevidence at protein level
Length862
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesArhgef7

GO terms

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GOName
GO:0000322 storage vacuole
GO:0001726 ruffle
GO:0002244 hematopoietic progenitor cell differentiation
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0007030 Golgi organization
GO:0007264 small GTPase mediated signal transduction
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030032 lamellipodium assembly
GO:0030426 growth cone
GO:0032092 positive regulation of protein binding
GO:0032991 protein-containing complex
GO:0043005 neuron projection
GO:0043015 gamma-tubulin binding
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0043615 astrocyte cell migration
GO:0060124 positive regulation of growth hormone secretion
GO:0097431 mitotic spindle pole
GO:0098794 postsynapse
GO:0098974 postsynaptic actin cytoskeleton organization
GO:0098982 GABA-ergic synapse
GO:0099140 presynaptic actin cytoskeleton organization
GO:1904424 regulation of GTP binding
GO:1905833 negative regulation of microtubule nucleation

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001452 SH3 domainDomainDomain
IPR001715 Calponin homology domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR032409 Rho guanine nucleotide exchange factor, coiled-coil domainDomainDomain
IPR035789 Rho guanine nucleotide exchange factor 7, SH3 domainDomainDomain
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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