Entity Details

Primary name STAT1
Entity type gene
Source Source Link

Details

PrimaryID6772
RefseqGeneNG_008294
SymbolSTAT1
Namesignal transducer and activator of transcription 1
Chromosome2
Location2q32.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsSTAT1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001937 negative regulation of endothelial cell proliferation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002230 positive regulation of defense response to virus by host
GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006952 defense response
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0008015 blood circulation
GO:0010742 macrophage derived foam cell differentiation
GO:0016032 viral process
GO:0016525 negative regulation of angiogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0019899 enzyme binding
GO:0030424 axon
GO:0030425 dendrite
GO:0032727 positive regulation of interferon-alpha production
GO:0032991 protein-containing complex
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034097 response to cytokine
GO:0035035 histone acetyltransferase binding
GO:0035456 response to interferon-beta
GO:0035458 cellular response to interferon-beta
GO:0038113 interleukin-9-mediated signaling pathway
GO:0038114 interleukin-21-mediated signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042981 regulation of apoptotic process
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043434 response to peptide hormone
GO:0044389 ubiquitin-like protein ligase binding
GO:0045296 cadherin binding
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046725 negative regulation by virus of viral protein levels in host cell
GO:0048471 perinuclear region of cytoplasm
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051591 response to cAMP
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060334 regulation of interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0061326 renal tubule development
GO:0070102 interleukin-6-mediated signaling pathway
GO:0070106 interleukin-27-mediated signaling pathway
GO:0070757 interleukin-35-mediated signaling pathway
GO:0071346 cellular response to interferon-gamma
GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development
GO:0072162 metanephric mesenchymal cell differentiation
GO:0072308 negative regulation of metanephric nephron tubule epithelial cell differentiation
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
STAT1Jak2BioGRID7657660 details
STAT1EgfrBioGRID7657660 details
STAT1Xpo1IntAct26673895 details
STAT1Dppa3BioGRID28712289 details