Entity Details

Primary name STAT3
Entity type gene
Source Source Link

Details

PrimaryID6774
RefseqGeneNG_007370
SymbolSTAT3
Namesignal transducer and activator of transcription 3
Chromosome17
Location17q21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsSTAT3_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001659 temperature homeostasis
GO:0001754 eye photoreceptor cell differentiation
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006606 protein import into nucleus
GO:0006952 defense response
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0007399 nervous system development
GO:0008134 transcription factor binding
GO:0010507 negative regulation of autophagy
GO:0010628 positive regulation of gene expression
GO:0016032 viral process
GO:0016310 phosphorylation
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0019953 sexual reproduction
GO:0030335 positive regulation of cell migration
GO:0030522 intracellular receptor signaling pathway
GO:0031490 chromatin DNA binding
GO:0032355 response to estradiol
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032733 positive regulation of interleukin-10 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032870 cellular response to hormone stimulus
GO:0033210 leptin-mediated signaling pathway
GO:0035019 somatic stem cell population maintenance
GO:0035723 interleukin-15-mediated signaling pathway
GO:0038111 interleukin-7-mediated signaling pathway
GO:0038113 interleukin-9-mediated signaling pathway
GO:0038114 interleukin-21-mediated signaling pathway
GO:0038155 interleukin-23-mediated signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042593 glucose homeostasis
GO:0042755 eating behavior
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043434 response to peptide hormone
GO:0044320 cellular response to leptin stimulus
GO:0044321 response to leptin
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0048708 astrocyte differentiation
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051726 regulation of cell cycle
GO:0060019 radial glial cell differentiation
GO:0060259 regulation of feeding behavior
GO:0060396 growth hormone receptor signaling pathway
GO:0060397 growth hormone receptor signaling pathway via JAK-STAT
GO:0070102 interleukin-6-mediated signaling pathway
GO:0070106 interleukin-27-mediated signaling pathway
GO:0070757 interleukin-35-mediated signaling pathway
GO:0070878 primary miRNA binding
GO:0071345 cellular response to cytokine stimulus
GO:0072538 T-helper 17 type immune response
GO:0072540 T-helper 17 cell lineage commitment
GO:0090575 RNA polymerase II transcription regulator complex
GO:0097009 energy homeostasis
GO:1900017 positive regulation of cytokine production involved in inflammatory response
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1904685 positive regulation of metalloendopeptidase activity
GO:1905618 positive regulation of miRNA mediated inhibition of translation
GO:2000635 negative regulation of primary miRNA processing
GO:2000637 positive regulation of gene silencing by miRNA

Diseases

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Interactions

6 interactions