Entity Details

Primary name AURKA
Entity type gene
Source Source Link

Details

PrimaryID6790
RefseqGeneNG_012133
SymbolAURKA
Nameaurora kinase A
Chromosome20
Location20q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAURKA_HUMAN

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005819 spindle
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005929 cilium
GO:0006468 protein phosphorylation
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007051 spindle organization
GO:0007052 mitotic spindle organization
GO:0007057 spindle assembly involved in female meiosis I
GO:0007100 mitotic centrosome separation
GO:0009611 response to wounding
GO:0009948 anterior/posterior axis specification
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0010629 negative regulation of gene expression
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0015630 microtubule cytoskeleton
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0030496 midbody
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031616 spindle pole centrosome
GO:0031625 ubiquitin protein ligase binding
GO:0031647 regulation of protein stability
GO:0032091 negative regulation of protein binding
GO:0032133 chromosome passenger complex
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032465 regulation of cytokinesis
GO:0035174 histone serine kinase activity
GO:0042585 germinal vesicle
GO:0043066 negative regulation of apoptotic process
GO:0043203 axon hillock
GO:0045120 pronucleus
GO:0045840 positive regulation of mitotic nuclear division
GO:0046605 regulation of centrosome cycle
GO:0046777 protein autophosphorylation
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0051233 spindle midzone
GO:0051301 cell division
GO:0051642 centrosome localization
GO:0071539 protein localization to centrosome
GO:0072687 meiotic spindle
GO:0097421 liver regeneration
GO:0097431 mitotic spindle pole
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900195 positive regulation of oocyte maturation
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1990138 neuron projection extension

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
AURKAIncenpBioGRID, IntAct11050385 20360068 details
AURKAOgnmatrixdb20375348 details
AURKASirt2BioGRID, IntAct22014574 details
AURKANek9BioGRID, IntAct20360068 details
AURKADab2UniProt22323290 details
AURKAPpp6r3IntAct24255178 details
AURKAXpo1IntAct26673895 details