Entity Details

Primary name TAP1
Entity type gene
Source Source Link

Details

PrimaryID6890
RefseqGeneNG_011759
SymbolTAP1
Nametransporter 1, ATP binding cassette subfamily B member
Chromosome6
Location6p21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-04-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTAP1_HUMAN

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005524 ATP binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006952 defense response
GO:0015031 protein transport
GO:0015433 ABC-type peptide antigen transporter activity
GO:0015440 ABC-type peptide transporter activity
GO:0015833 peptide transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016032 viral process
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 MHC class Ib protein binding
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030670 phagocytic vesicle membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0034451 centriolar satellite
GO:0042288 MHC class I protein binding
GO:0042605 peptide antigen binding
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042803 protein homodimerization activity
GO:0042824 MHC class I peptide loading complex
GO:0042825 TAP complex
GO:0043531 ADP binding
GO:0046872 metal ion binding
GO:0046967 cytosol to endoplasmic reticulum transport
GO:0046978 TAP1 binding
GO:0046979 TAP2 binding
GO:0055085 transmembrane transport
GO:1904680 peptide transmembrane transporter activity
GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
TAP1Bmpr1aBioGRID, IntAct26496610 details
TAP1Rab5cBioGRID, IntAct26496610 details
TAP1Sidt2BioGRID, IntAct26496610 details
TAP1Tubgcp5BioGRID, IntAct26496610 details
TAP1Tmed2BioGRID, IntAct26496610 details
TAP1ArBioGRID, IntAct26496610 details