Entity Details

Primary name TCF7L2
Entity type gene
Source Source Link

Details

PrimaryID6934
RefseqGeneNG_012631
SymbolTCF7L2
Nametranscription factor 7 like 2
Chromosome10
Location10q25.2-q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-01-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTF7L2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001568 blood vessel development
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0009749 response to glucose
GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0016605 PML body
GO:0019901 protein kinase binding
GO:0031016 pancreas development
GO:0032024 positive regulation of insulin secretion
GO:0032092 positive regulation of protein binding
GO:0032350 regulation of hormone metabolic process
GO:0032993 protein-DNA complex
GO:0042593 glucose homeostasis
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0043570 maintenance of DNA repeat elements
GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
GO:0045295 gamma-catenin binding
GO:0045444 fat cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046827 positive regulation of protein export from nucleus
GO:0048625 myoblast fate commitment
GO:0048660 regulation of smooth muscle cell proliferation
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051897 positive regulation of protein kinase B signaling
GO:0060070 canonical Wnt signaling pathway
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0070016 armadillo repeat domain binding
GO:0070369 beta-catenin-TCF7L2 complex
GO:0071664 catenin-TCF7L2 complex
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1904837 beta-catenin-TCF complex assembly
GO:1990907 beta-catenin-TCF complex
GO:2000675 negative regulation of type B pancreatic cell apoptotic process
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TCF7L2Ctnnb1BioGRID, IntAct12417018 22014570 details