Entity Details

Primary name TERF2
Entity type gene
Source Source Link

Details

PrimaryID7014
RefseqGene
SymbolTERF2
Nametelomeric repeat binding factor 2
Chromosome16
Location16q22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTERF2_HUMAN

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000781 chromosome, telomeric region
GO:0000783 nuclear telomere cap complex
GO:0001673 male germ cell nucleus
GO:0001701 in utero embryonic development
GO:0003691 double-stranded telomeric DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007004 telomere maintenance via telomerase
GO:0008022 protein C-terminus binding
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016233 telomere capping
GO:0016604 nuclear body
GO:0019899 enzyme binding
GO:0031627 telomeric loop formation
GO:0031848 protection from non-homologous end joining at telomere
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032204 regulation of telomere maintenance
GO:0032205 negative regulation of telomere maintenance
GO:0032206 positive regulation of telomere maintenance
GO:0032208 negative regulation of telomere maintenance via recombination
GO:0032210 regulation of telomere maintenance via telomerase
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032214 negative regulation of telomere maintenance via semi-conservative replication
GO:0042162 telomeric DNA binding
GO:0042803 protein homodimerization activity
GO:0044877 protein-containing complex binding
GO:0045007 depurination
GO:0048239 negative regulation of DNA recombination at telomere
GO:0051000 positive regulation of nitric-oxide synthase activity
GO:0061820 telomeric D-loop disassembly
GO:0070187 shelterin complex
GO:0070198 protein localization to chromosome, telomeric region
GO:0090398 cellular senescence
GO:0098505 G-rich strand telomeric DNA binding
GO:0099087 anterograde axonal transport of messenger ribonucleoprotein complex
GO:1900051 positive regulation of histone exchange
GO:1903770 negative regulation of beta-galactosidase activity
GO:1903824 negative regulation of telomere single strand break repair
GO:1904115 axon cytoplasm
GO:1904354 negative regulation of telomere capping
GO:1904357 negative regulation of telomere maintenance via telomere lengthening
GO:1904430 negative regulation of t-circle formation
GO:1905778 negative regulation of exonuclease activity
GO:1905839 negative regulation of telomeric D-loop disassembly
GO:2000773 negative regulation of cellular senescence

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
TERF2Ppp1r10BioGRID, DIP, IntAct19287395 20360068 details
TERF2Terf1BioGRID, IntAct26496610 details
TERF2Cdkn2aipBioGRID, IntAct26496610 details
TERF2Dclre1bBioGRID, IntAct26496610 details