Entity Details

Primary name TFAP2A
Entity type gene
Source Source Link

Details

PrimaryID7020
RefseqGeneNG_016151
SymbolTFAP2A
Nametranscription factor AP-2 alpha
Chromosome6
Location6p24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAP2A_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001822 kidney development
GO:0003404 optic vesicle morphogenesis
GO:0003409 optic cup structural organization
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007605 sensory perception of sound
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010842 retina layer formation
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0021559 trigeminal nerve development
GO:0021623 oculomotor nerve formation
GO:0030501 positive regulation of bone mineralization
GO:0035115 embryonic forelimb morphogenesis
GO:0042127 regulation of cell population proliferation
GO:0042472 inner ear morphogenesis
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045595 regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048856 anatomical structure development
GO:0060021 roof of mouth development
GO:0060349 bone morphogenesis
GO:0061029 eyelid development in camera-type eye
GO:0070172 positive regulation of tooth mineralization
GO:0071281 cellular response to iron ion
GO:0140536 nuclear receptor corepressor activity
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000378 negative regulation of reactive oxygen species metabolic process

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
TFAP2AFcho2BioGRID20448150 details
TFAP2ACdc6BioGRID, IntAct26496610 details
TFAP2ANaa50BioGRID, IntAct26496610 details
TFAP2AGsk3bBioGRID, IntAct26496610 details