Entity Details

Primary name DYSF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ESD7
EntryNameDYSF_MOUSE
FullNameDysferlin
TaxID10090
Evidenceevidence at protein level
Length2090
SequenceStatuscomplete
DateCreated2002-01-23
DateModified2021-06-02

Ontological Relatives

GenesDysf

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001778 plasma membrane repair
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002280 monocyte activation involved in immune response
GO:0002281 macrophage activation involved in immune response
GO:0005509 calcium ion binding
GO:0005543 phospholipid binding
GO:0005544 calcium-dependent phospholipid binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0006071 glycerol metabolic process
GO:0006906 vesicle fusion
GO:0007009 plasma membrane organization
GO:0008017 microtubule binding
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0019915 lipid storage
GO:0030027 lamellipodium
GO:0030139 endocytic vesicle
GO:0030315 T-tubule
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0033292 T-tubule organization
GO:0034451 centriolar satellite
GO:0042177 negative regulation of protein catabolic process
GO:0042383 sarcolemma
GO:0043014 alpha-tubulin binding
GO:0043403 skeletal muscle tissue regeneration
GO:0045444 fat cell differentiation
GO:0045785 positive regulation of cell adhesion
GO:0050765 negative regulation of phagocytosis
GO:0061025 membrane fusion
GO:0071470 cellular response to osmotic stress
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0090279 regulation of calcium ion import
GO:0098857 membrane microdomain
GO:1901842 negative regulation of high voltage-gated calcium channel activity
GO:1902915 negative regulation of protein polyubiquitination

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic vesicle membrane

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR006614 Peroxin/Ferlin domainDomainDomain
IPR012560 Ferlin A-domainDomainDomain
IPR012561 Ferlin B-domainDomainDomain
IPR012968 FerIin domainDomainDomain
IPR029998 DysferlinFamilyFamily
IPR032362 Ferlin, C-terminal domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR037720 Ferlin, second C2 domainDomainDomain
IPR037721 Ferlin familyFamilyFamily
IPR037722 Ferlin, third C2 domainDomainDomain
IPR037723 Ferlin, fourth C2 domainDomainDomain
IPR037724 Ferlin, fifth C2 domainDomainDomain
IPR037725 Ferlin, sixth C2 domainDomainDomain
IPR037726 Ferlin, first C2 domainDomainDomain

Diseases

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Interactions

4 interactions