Entity Details

Primary name OTOF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ESF1
EntryNameOTOF_MOUSE
FullNameOtoferlin
TaxID10090
Evidenceevidence at protein level
Length1997
SequenceStatuscomplete
DateCreated2002-01-23
DateModified2021-06-02

Ontological Relatives

GenesOtof

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001964 startle response
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0007009 plasma membrane organization
GO:0007605 sensory perception of sound
GO:0016021 integral component of membrane
GO:0016079 synaptic vesicle exocytosis
GO:0016082 synaptic vesicle priming
GO:0016323 basolateral plasma membrane
GO:0030672 synaptic vesicle membrane
GO:0035612 AP-2 adaptor complex binding
GO:0042995 cell projection
GO:0044877 protein-containing complex binding
GO:0045177 apical part of cell
GO:0045178 basal part of cell
GO:0048787 presynaptic active zone membrane

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell junction
Cell membrane
Cytoplasmic vesicle
Endoplasmic reticulum membrane
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR012561 Ferlin B-domainDomainDomain
IPR012968 FerIin domainDomainDomain
IPR029996 OtoferlinFamilyFamily
IPR032362 Ferlin, C-terminal domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR037720 Ferlin, second C2 domainDomainDomain
IPR037721 Ferlin familyFamilyFamily
IPR037722 Ferlin, third C2 domainDomainDomain
IPR037723 Ferlin, fourth C2 domainDomainDomain
IPR037724 Ferlin, fifth C2 domainDomainDomain
IPR037725 Ferlin, sixth C2 domainDomainDomain
IPR037726 Ferlin, first C2 domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
OTOF_MOUSESTK39_MOUSEBioGRID, IntAct14563843 32325033 details