Entity Details

Primary name TLE1
Entity type gene
Source Source Link

Details

PrimaryID7088
RefseqGene
SymbolTLE1
NameTLE family member 1, transcriptional corepressor
Chromosome9
Location9q21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsTLE1_HUMAN

GO terms

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GOName
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0007275 multicellular organism development
GO:0008134 transcription factor binding
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0042802 identical protein binding
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045892 negative regulation of transcription, DNA-templated
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1904837 beta-catenin-TCF complex assembly
GO:1990907 beta-catenin-TCF complex
GO:2000811 negative regulation of anoikis

Diseases

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Interactions

6 interactions