Entity Details

Primary name TOP2B
Entity type gene
Source Source Link

Details

PrimaryID7155
RefseqGeneNG_052961
SymbolTOP2B
NameDNA topoisomerase II beta
Chromosome3
Location3p24.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-05-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTOP2B_HUMAN

GO terms

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GOName
GO:0000712 resolution of meiotic recombination intermediates
GO:0000819 sister chromatid segregation
GO:0001764 neuron migration
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006265 DNA topological change
GO:0007409 axonogenesis
GO:0008022 protein C-terminus binding
GO:0019899 enzyme binding
GO:0030900 forebrain development
GO:0042826 histone deacetylase binding
GO:0045870 positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:1990904 ribonucleoprotein complex

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
TOP2BTop2bBioGRID, IntAct20360068 details
TOP2BCbx1BioGRID, IntAct26496610 details
TOP2BAtrxBioGRID, IntAct26496610 details
TOP2BEef1a1BioGRID, IntAct26496610 details
TOP2BRrbp1BioGRID, IntAct26496610 details
TOP2BEif3eBioGRID, IntAct26496610 details
TOP2BPrdm16MINT30462309 details
TOP2BMecomMINT30462309 details