Entity Details

Primary name TP53BP1
Entity type gene
Source Source Link

Details

PrimaryID7158
RefseqGene
SymbolTP53BP1
Nametumor protein p53 binding protein 1
Chromosome15
Location15q15.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-20
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsTP53B_HUMAN

GO terms

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GOName
GO:0000077 DNA damage checkpoint signaling
GO:0000781 chromosome, telomeric region
GO:0002039 p53 binding
GO:0003684 damaged DNA binding
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005657 replication fork
GO:0005737 cytoplasm
GO:0006302 double-strand break repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006974 cellular response to DNA damage stimulus
GO:0016604 nuclear body
GO:0035064 methylated histone binding
GO:0035861 site of double-strand break
GO:0042162 telomeric DNA binding
GO:0042393 histone binding
GO:0045830 positive regulation of isotype switching
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051260 protein homooligomerization
GO:0061649 ubiquitin modification-dependent histone binding
GO:0071481 cellular response to X-ray
GO:1990391 DNA repair complex
GO:2000042 negative regulation of double-strand break repair via homologous recombination

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
TP53BP1Trp53BioGRID16169070 details
TP53BP1Paxip1UniProt17500065 17925232 19124460 details
TP53BP1H2axBioGRID12792649 details
TP53BP1Dynll1BioGRID, IntAct20360068 details
TP53BP1ScaiBioGRID, IntAct26496610 details