Entity Details

Primary name TP73
Entity type gene
Source Source Link

Details

PrimaryID7161
RefseqGeneNG_017035
SymbolTP73
Nametumor protein p73
Chromosome1
Location1p36.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-13
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsP73_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001822 kidney development
GO:0002039 p53 binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006298 mismatch repair
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006974 cellular response to DNA damage stimulus
GO:0007346 regulation of mitotic cell cycle
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010243 response to organonitrogen compound
GO:0010468 regulation of gene expression
GO:0016032 viral process
GO:0019901 protein kinase binding
GO:0030054 cell junction
GO:0042493 response to drug
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0045665 negative regulation of neuron differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0051262 protein tetramerization
GO:0060044 negative regulation of cardiac muscle cell proliferation
GO:0097371 MDM2/MDM4 family protein binding
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1902036 regulation of hematopoietic stem cell differentiation

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
TP73Sumo1MINT10961991 details
TP73Cables1IntAct11706030 details
TP73Yap1MINT11278685 details