Entity Details

Primary name TRAF3
Entity type gene
Source Source Link

Details

PrimaryID7187
RefseqGeneNG_027973
SymbolTRAF3
NameTNF receptor associated factor 3
Chromosome14
Location14q32.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-05-05
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsTRAF3_HUMAN

GO terms

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GOName
GO:0001817 regulation of cytokine production
GO:0002224 toll-like receptor signaling pathway
GO:0004842 ubiquitin-protein transferase activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005739 mitochondrion
GO:0005768 endosome
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0008063 Toll signaling pathway
GO:0008270 zinc ion binding
GO:0009898 cytoplasmic side of plasma membrane
GO:0016579 protein deubiquitination
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0030162 regulation of proteolysis
GO:0031625 ubiquitin protein ligase binding
GO:0031996 thioesterase binding
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032648 regulation of interferon-beta production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035631 CD40 receptor complex
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0046330 positive regulation of JNK cascade
GO:0050688 regulation of defense response to virus
GO:0070534 protein K63-linked ubiquitination

Diseases

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Interactions

5 interactions