Entity Details

Primary name ING2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ESK4
EntryNameING2_MOUSE
FullNameInhibitor of growth protein 2
TaxID10090
Evidenceevidence at protein level
Length281
SequenceStatuscomplete
DateCreated2005-02-15
DateModified2021-06-02

Ontological Relatives

GenesIng2

GO terms

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GOName
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0007141 male meiosis I
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0008285 negative regulation of cell population proliferation
GO:0016580 Sin3 complex
GO:0016602 CCAAT-binding factor complex
GO:0030317 flagellated sperm motility
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031065 positive regulation of histone deacetylation
GO:0035064 methylated histone binding
GO:0035091 phosphatidylinositol binding
GO:0040008 regulation of growth
GO:0044877 protein-containing complex binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0048133 male germ-line stem cell asymmetric division
GO:0072520 seminiferous tubule development
GO:2000772 regulation of cellular senescence
GO:2001234 negative regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR024610 Inhibitor of growth protein, N-terminal histone-bindingDomainDomain
IPR028639 Inhibitor of growth protein 2FamilyFamily
IPR028651 ING familyFamilyFamily
IPR042019 ING2, PHD domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ING2_MOUSEH33_MOUSEBioGRID16728977 details
ING2_MOUSESMAD1_HUMANMINT15761153 details