Entity Details

Primary name DUS10_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ESS0
EntryNameDUS10_MOUSE
FullNameDual specificity protein phosphatase 10
TaxID10090
Evidenceevidence at transcript level
Length483
SequenceStatuscomplete
DateCreated2003-05-09
DateModified2021-06-02

Ontological Relatives

GenesDusp10

GO terms

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GOName
GO:0000188 obsolete inactivation of MAPK activity
GO:0002819 regulation of adaptive immune response
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0008330 protein tyrosine/threonine phosphatase activity
GO:0008432 JUN kinase binding
GO:0010633 negative regulation of epithelial cell migration
GO:0016311 dephosphorylation
GO:0016607 nuclear speck
GO:0016791 phosphatase activity
GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0032496 response to lipopolysaccharide
GO:0032873 negative regulation of stress-activated MAPK cascade
GO:0033549 MAP kinase phosphatase activity
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035970 peptidyl-threonine dephosphorylation
GO:0043508 negative regulation of JUN kinase activity
GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045088 regulation of innate immune response
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0046329 negative regulation of JNK cascade
GO:0048273 mitogen-activated protein kinase p38 binding
GO:0048709 oligodendrocyte differentiation
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051019 mitogen-activated protein kinase binding
GO:0060266 negative regulation of respiratory burst involved in inflammatory response
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0090335 regulation of brown fat cell differentiation
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1903753 negative regulation of p38MAPK cascade
GO:1905042 negative regulation of epithelium regeneration
GO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR001763 Rhodanese-like domainDomainDomain
IPR008343 Mitogen-activated protein (MAP) kinase phosphataseFamilyFamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR020422 Dual specificity protein phosphatase domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036873 Rhodanese-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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