Entity Details

Primary name NR1H2
Entity type gene
Source Source Link

Details

PrimaryID7376
RefseqGene
SymbolNR1H2
Namenuclear receptor subfamily 1 group H member 2
Chromosome19
Location19q13.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNR1H2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0008270 zinc ion binding
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0010875 positive regulation of cholesterol efflux
GO:0010884 positive regulation of lipid storage
GO:0010887 negative regulation of cholesterol storage
GO:0030154 cell differentiation
GO:0030522 intracellular receptor signaling pathway
GO:0031667 response to nutrient levels
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032369 negative regulation of lipid transport
GO:0032376 positive regulation of cholesterol transport
GO:0034191 apolipoprotein A-I receptor binding
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0042632 cholesterol homeostasis
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0045861 negative regulation of proteolysis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046965 retinoid X receptor binding
GO:0048384 retinoic acid receptor signaling pathway
GO:0048550 negative regulation of pinocytosis
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0051117 ATPase binding
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
GO:0090108 positive regulation of high-density lipoprotein particle assembly
GO:0090187 positive regulation of pancreatic juice secretion
GO:0090340 positive regulation of secretion of lysosomal enzymes
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1903573 negative regulation of response to endoplasmic reticulum stress

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NR1H2Senp3DIP21331046 details
NR1H2Coro2aDIP21331046 details